House of Nutrition S23:
S-23 was found to have a half life of 11.9 hours with 96% of it being absorbed. The peak levels in this research started roughly four hours after administration of the SARM. S-23 works by binding to proteins of the androgen receptors. By doing so it is able to activate muscle building within the body. Currently no human studies are available. However, in a report on a study done with rats, researchers noted that S-23 was able to prevent muscle loss through receptors known as glucocorticoid.
All products currently listed on this site are for research purposes only and not for human consumption.
SARMs are not evaluated by the FDA, nor are they allowed by WADA.
|Application:||Binds to androgen receptors|
|Molecular Weight:||416.76g mol|
|Chemical Name:||(S)-N-(4-Cyano-3-Trifluoromethyl-Phenyl)-3-(3-Fluoro, 4-Chlorophenoxy)-2-Hydroxy-2-Methyl-Propanamide|
|Synonyms:||1010396-29-8, CCTH-methylpropionamide, UNII-XDK89456WM, CHEMBL512283|
|Storage:||Minimize open air exposure, store in a cool dry place.|
|Solubility:||Soluble to ethanol at rate of 10mg/ml|
|Organoleptic Profile:||slightly yellow, crystalline powder.|
|Physical Form:||fine powder in vegan capsule|
|Container:||60 Andarine S-4 capsules|
|Terms:||The products we offer are intended for laboratory research use only.|
S23 is growing in popularity as one of the more potent SARMs available to date. It has many benefits for its users. This includes both bone density and muscle mass improvements. Not only that, S-23 SARM has shown an affinity to aid female’s that have lost their sex drive. You can buy S23 from Paradigm Peptides in 5mg capsule form. If you’d like to learn more then read on in the description section.
S-23 – What Should You Know
S23 is a selective androgen receptor modulator, or SARM. Unlike other compounds such as Andarine, it is able to bind more thoroughly to androgen receptors. The compound was developed by GTx, Inc. GTx is a pharmaceutical company that specializes in both production of SARMs and SERMs. It was originally found in Memphis in 1997 and originally called Genotherapeutics. It didn’t become GTx until 2001.
What is S23?
As said above, SARMs are selective in nature. The point is to have compounds that mimic testosterone. This is done by binding to very specific receptors within the body. S23 is no different in its workings and it is said that it targets bone and muscle tissue much like other SARMs. It is one of the more potent SARMs available on the market. This is because of its ability to connect and create strong bonds with androgen receptors. By binding to androgen receptors, there is an increase in activity for muscle building proteins. This then creates an increase of muscle for the user.
As far as the half life of S-23, in animal studies it is at 11.9 hours with about 96% of it being absorbed. The peak levels start around the four hour mark for this SARM. As of right now, there are no human studies that have been conducted.
Benefits of S23
With a study done on rats, it was shown to decrease the average body weight and fat mass of the study subjects. In addition to this, estrogen was given to the rats as a way to promote mating. In doing this, muscle mass was lost. However, the SARM in turn was able to override the effects of the estrogen and produced more lean muscle mass in the rats. The benefits of fat decrease are dose dependent. Typically, the higher the dose, the better the results.
Another study revolved around glucocorticoid. These are receptors that transmit signals for things like cortisol. For those rats, S23 was able to prevent muscle loss because of glucocorticoid.
Of course, it’s not all about muscle as bones can be affected too. Of course, this is typically in a positive manner. In other animal studies, it increased bone mineral density like many other SARMs do.
Something to think about is that this particular SARM is being researched as a male birth control option. But don’t worry, this doesn’t mean that you will fully lose your ability to have children. In fact, it works much in the same way the female birth control pill works. It reduces hormones such as LH and FSH. This by default suppresses sperm production. The rest is pretty self-explanatory. Once you discontinue use, your hormone levels typically return to normal and you are good to go.
A final benefit is the potential for S-23 to increase sexual desire in women. In a study with female postmenopausal rats, it increased sexual desire and maintained the size of the female rat’s uterus and uterine lining.
Side Effects of S23
Side effects for this SARM are still being determine. However, some of the common ones include night sweats, cramping, an increase in both aggression and acne as well as the possibility of hair loss. Of course, many of these side effects are mild in nature and do tend to dissipate over time.
The Right S-23 Dosage
For bodybuilders looking to reach higher gains, the dosage protocol is pretty straight forward. Dosages are usually between 10mg and 30mg. The basics of using S23 is to start on the lower end of dosing so that you can see how it effects the body. Then once your baseline is established, you can increase the dose without going past the 30mg mark. There are two variations of cycles currently used.
Bulking and Cutting with S-23
Unlike most other SARMs that typically stay around the eight week mark for cycle length. S23 has been known to be taken for up to twelve weeks and usually involves a PCT at that point. For the sake of bulking up, the first couple of weeks you would take 10mg per day to get your body used to the compound. Then once your body is used to the compound you can up the dose to 30mg per day. This would be taken as two or three doses throughout the day. This would mean either three doses of 10mg or two doses of 15mg.
If you end your cycle at the eight week mark, a PCT is not necessarily needed. However, say you go the full 12 weeks, you’ll want to complete a PCT with both Clomiphene Citrate and Tamoxifen Citrate. As for doses of these substances, Tamoxifen Citrate should be taken at 20mg per day and Clomiphene Citrate should be taken at 25mg per day.
Commonly MK 766 can be stacked with S23 if you’d like to increase your performance enhancement and boost your bulk.
Cutting is the same dosage protocol as stacking. The largest difference is that you’re creating a calorie deficit. Of course, if you’re looking for a little more to the cutting cycle stacking is an option. Instead of stacking MK 677 with it, you would stack GW501516, MK2866, or S4 instead. In either case, you would need to complete at least a two week PCT.